Clindamycin 1) Chemical Name: * methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate) 2) Drug name and nobleman: * The dose name is Cleocin. Clindamycin is manufacture by several unlike companies which include Teuto, Ranbaxy, and Stiefel. 3) Mechanism of process: * Clindamycin is employ to call heartbreaking transmittances ca intentd by anaerobiotic bacteria. Clindamycin is withal prescribed to treat malignant infections due to strains of streptococci, pneumococci, and staphylococci. Clindamycin is an anti-parasitic medicine that is prescribed to treat toxoplasmosis. Also, much it is apply as investigational treatment for active PCP pneumonia. It as well treats respiratory tract infections. If you atomic number 18 allergic to penicillin, or should not use penicillin match to a medical student, then clindamycin should be utilize specifically for these patients. collect to a risk of colitis, according to the warning on the prescription, a doctor should choose other less cyanogenic alternatives if the infection isnt as serious. An example would be erythromycin. To lessen the cherish the sustainability of Cleocin, it should moreover be used to bring to or go on infections and fungi that ar decidedly precedentd by vulnerable bacteria. 4) cause apart or broad Spectrum: Narrow Spectrum 5) What organisms is this antibiotic for? * oxidative positive cocci, including: staphylococcus aureus, Staphylococcus epidermidis, when tested by in vitro methods close to staphylococcal strains originally resistant to erythromycin quickly cause resistance to clindamycin, streptococcus (except Streptococcus faecalis), Pneumococci. * anaerobic negative bacilli, including: genus Bacteroides species (including Bacteroides fragilis crowd and Bacteroides melaninogenucus group), Fusobacterium species. * Anaerobic confirming non spore forming bacilli, including: Propionibacterium, Eubacterium, Actinomyces species. Anaerobic and microaerophilic gram-positive cocci, including: Peptococcus species, Peptostreptococcus species, Microaerophilic streptococci. 6) How is it administered? Clindamycin fag end be administered in 3 mixed steps. Also, for the best results, rally to carry on the antibiotic on a daily basis. * Orally Take both with a meal or without a meal. Remember that if you are experiencing stomach pains, take with food. taking it with a full chicken feed of water is also optional. * vaginal Application - demarcation that the cream seat only be used in this area. It may cause burning, and above all do not beget sexual intercourse while victimization this drug. * peel off Application Not to be taken by mouth. practical application should be agitate preliminary to application. Remove pledget from foil and right off throw away. take halal hygiene and wash work force before and afterward use. give only a cut back strip of jelly to rid of irritation. Bandages, make-up, etc should not be use until consulting a doctor for advice. 7) every toxicities, or side make? Â Â Â Â Â Â Â Â Abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting and diarrhea.
generalized soft to moderate morbilliform-like (maculopapular) skin rashes, Vesiculobullous rashes, urticaria, have been find during drug therapy. archaic instances of erythema muttiforme, some resembling Stevens-Johnson syndrome, and a a couple of(prenominal) cases of anaphylactoid reactions have also been reported. acrimony and abnormalities in liver buy the farm tests have been observed during clindamycin therapy. short-lived neutropenia (leukopenia) and eosinophilia have been reported. Clindamycin has been shown to have neuromuscular blocking properties that may nurture the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving much(prenominal) agents. Opposition has been corroborate betwixt clindamycin and erythromycin. Do not take these antibiotics at the aforesaid(prenominal) time. References: 1) Retrieved February 22, 2006, from MedlinePlus Drug info net situation: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682399.html#brand-names 2) Retrieved February 22, 2006, from ADAP drugs network come in: http://www.atdn.org/access/drugs/clin.html 3) Retrieved February 22, 2006, from clindamycin commonly used music for human immunodeficiency virus & AIDS patients vane rate: http://www.hivdent.org/drugs/clindamycin.htm 4) Retrieved February 22, 2006, from medicament instructions for clindamycin Web site: http://www1.va.gov/visn10/CincyMedSheets/Clindamycin.htm 5) Retrieved February 22, 2006, from Clindamycin Web site: http://www.clindamycin.com/ If you want to get a full essay, enunciate it on our website:
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